ABSTRACT
Since December 2019, the novel coronavirus disease (COVID-19) has had a considerable impact on the health and socio-economic fabric of Italy. The effective reproduction number Rt is one of the most representative indicators of the contagion status as it reports the number of new infections caused by an infected subject in a partially immunized population. The task of predicting Rt values forward in time is challenging and, historically, it has been addressed by exploiting compartmental models or statistical frameworks. The present study proposes an Artificial Neural Networks-based approach to predict the Rt temporal trend at a daily resolution. For each Italian region and autonomous province, 21 daily COVID-19 indicators were exploited for the 7-day ahead prediction of the Rt trend by means of different neural network architectures, i.e., Feed Forward, Mono-Dimensional Convolutional, and Long Short-Term Memory. Focusing on Lombardy, which is one of the most affected regions, the predictions proved to be very accurate, with a minimum Root Mean Squared Error (RMSE) ranging from 0.035 at day t + 1 to 0.106 at day t + 7. Overall, the results show that it is possible to obtain accurate forecasts in Italy at a daily temporal resolution instead of the weekly resolution characterizing the official Rt data.